Primary Care doc, likes research, teaches residents,
#HSR,
#MEPS,
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this is a letter to the editor from a high school track runner who came in second to a trans girl in a race. her state house rep in maine started talking about it. so she wrote this:
www.pressherald.com/2025/05/14/r...[Not loaded yet]
Hear me out. We divide the country into twelve regions, call them districts. Then we take two kids from each district and have them battle to the death in an arena . . .
Kristi Noem has been working with the producer of “Duck Dynasty” to pitch a reality TV show—titled “The American”—where immigrants will compete in a string of challenges across the country “for the honor of fast-tracking their way to U.S. citizenship,” according to a new report.
Noem Plots Reality Show Where Migrants Fight for Citizenship
A Homeland Security official told the Daily Beast that the show is in the early stages of vetting, though approval has not been given—or denied.
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@mdaware.org Favorite scene from
#Andor season #2. The hospital administrator.
Oveporexton, an Oral Orexin Receptor 2–Selective Agonist, in Narcolepsy Type 1 | NEJM
Narcolepsy type 1 is a disorder of hypersomnolence caused by a loss of orexin neurons, which results in low orexin levels in the brain. In this phase 2, randomized, placebo-controlled trial, partic...
Important stuff and not at all suprising.
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wow
Ok frequentists, let’s call a truce. This has gone too far.
They really think their mass firings had nothing to do with the problems we’re now seeing.
Alsobrooks: You’ve cut the Special Olympics
RFK Jr.: No we didn’t
Alsobrooks: You’ve cut all of the funding for it.
Senator Alsobrooks: You’ve been unable to address specific questions about your agency. Can you name which office the Safe to Sleep program operates out of?
RFK Jr.: Guesses wrong 5 times
Alsobrooks: It is the Eunice Kennedy Shriver NICHD.
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Dedra and Syril is a contender for my favorite Star Wars story line of all time.
#andorWe never really saw an extreme drop in Chinese container volumes to the US, they held up *way* better than I expected over the past month.
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"Associations" are just bad descriptive studies.
No-one cares whether smartphone use, or any other exposure, is ASSOCIATED with health!
This tells us nothing of practical use.
The only thing we should care about finding out is to what extent smartphone use, or any other exposure, CAUSE mental health.
STOP ESTIMATING ASSOCIATIONS!
Letter to America: A Rewilding - Terrain.org
Christienne L. Hinz's delightful Letter to America reviews the history of rewilding her southern Illinois yard under the eye of the White Gaze.
There you have it: BEDMED published in
@jama.com
jamanetwork.com/journals/jam...
h/t
@drjmluther.bsky.social
No difference in bedtime versus morning BP meds - as expected
#NephSky #Hypertension
1/
Am I the only one who remembers this?
Thanks to everybody who chimed in!
I arrived at the conclusion that (1) there's a lot of interesting stuff about interactions and (2) the figure I was looking for does not exist.
So, I made it myself! Here's a simple illustration of how to control for confounding in interactions:>
Does anybody have a good visualization to explain how interactions can be confounded, and why interactions require interaction controls?
@urisohn.bsky.social maybe?
(Asking because I have an idea, but want to check out what exists already before investing the effort)
Thread? THREAD! Let's look at Surmount 5. Tirzepatide vs Semaglutide. What's better? What's the same? What does it mean for the future of obesity medicine?
I'm using slides from today's presentation at
#ECO2025 and from the NEJM paper & supplementary appendix(always read the appendix!)
-
View full thread
Clearly Tirz is the better drug across multiple indicators.
I also like the idea of Treat to Target especially as someone prescribing these drugs. Getting a normalized BMI and WHtR is easy to explain to patients for risk reductions. So for now we can crown Tirz as king.
Speaking of fibrates and putting yet another nail in their coffin. Tirzepatide. 30% decrease in TGs in Surmount 5
On CVD topic, because it's a "dirty" drug it'll be hard, maybe impossible to figure out what's helping & what's hurting. But I'll consider prescribing it for certain CVD patients
Colchicine to prevent arterial disease is fascinating. Clear evidence of benefit to prevent vascular events with no hint of mortality benefit (cardiovascular or not).
academic.oup.com/eurheartj/ad...
Long-term trials of colchicine for secondary prevention of vascular events: a meta-analysis
AbstractBackground and Aims. Colchicine has emerged as a safe and inexpensive anti-inflammatory medication to target the residual risk of cardiovascular ev
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Major progress reported in Punching Each Other In The Face For No Reason Talks as both sides agree to temporarily punch one another in the kidneys for a while instead.
Health policy genius.
In ranking things, we were 99.5% sure about: I present you this.
Freedom for me; not for thee.
"Let parents decide on whether to vaccinate their kids" was just a lie.
It’s amazing how this 25-year-old system was working fine *right* up to the point where DOGE started fucking with it, and then it suddenly broke.
They’re like arsonists who set fires so just they can rush in and save people
Duffy on the air traffic control system: "The lights are blinking, the sirens are turning ... what you see in Newark is gonna happen in other places across the country."
Good luck, air travelers!
Algorithims always win.
Negativity bias means that bad news spreads and gets recommended more. Meaning that incumbency effects might actually be negative for the president now? Regardless recommendation divorced from social graph has probably made the thermostat much more sensitive.
When he sees this he's gonna be so embarrassed
Article I, Section 9, Clause 8:
“no Person holding any Office of Profit or Trust under them, shall, without the Consent of the Congress, accept of any present, Emolument, Office, or Title, of any kind whatever, from any King, Prince, or foreign State.”
Qatar-a-Lago
For the umpteenth - but almost certainly not last time - the institutions of the American economy depend on the institutions of American democracy.
I really don't see how rights are irrelevant because the economy is all that matters.
Even if you think the economy is by far the most important thing, rights are a crucial part of a well-functioning economy. The White House's attack on rights in the US is bad on it's own AND harming the economy.
Holy shiitake! Trump fired Shira Perlmutter, the Director of the US Copyrights Office apparently because she refused to let Elon Musk raid the place to steal author’s intellectual property rights
democrats-cha.house.gov/media/press-...Seems important.
NEW ODD LOTS:
Why the world keeps getting surprised by Chinese tech gains.
@tracyalloway.bsky.social and I speak with
@kaiserkuo.bsky.social, host of the Sinica podcast
podcasts.apple.com/us/podcast/w...
Why the World Keeps Getting Shocked by China's Technological Progress
Podcast Episode · Odd Lots · 05/10/2025 · 39m
White House blasts Dems ‘crossing the line’ by storming ICE facility
The White House slammed Democrats after three Congress members stormed into a New Jersey ICE prison for an "oversight visit." The prison is full of alleged dangerous criminals.
I just really need everybody to understand that everything that’s happening in and to the global economy now (and all the businesses and people in it) is the entirely predictable result of the intentional decisions of one guy who doesn’t understand how the global economy works.
Single payer isn't always the solution.
The NHS in England is planning "previously unthinkable" cuts to try to balance the books, health bosses say.
Services including diabetes care for young people, rehab centres and talking therapies are in the firing line, according to NHS Providers
www.bbc.co.uk/news/article...
NHS plans 'unthinkable' cuts to balance books
Diabetes care, rehab centres, end-of-life services and talking therapies at risk in England.
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"What did they do?" -- Trump has no idea what he's signing and has to have it explained to him
This thread is about SW, but really it's about modern popular entertainment generally. With the internet & social media, everything is on the surface, transparent. Creators operate under constant scrutiny, with fans constantly demanding this or that.
The regime just arrested the Mayor of Newark. We're in the phase of attempted fascist takeover where opposition elected officials are subject to arbitrary arrest.
Alina Habba, Trump’s personal lawyer and now the interim U.S. attorney for NJ, announces that the Trump administration has arrested the mayor of Newark at an private prison that ICE had decently contracted as a detention center. His arrest is seemingly for trespass.
US FDA approves first at-home test for cervical cancer screening
reut.rs/3GZu50G
US FDA approves first at-home test for cervical cancer screening
The U.S. Food and Drug Administration has approved the first at-home test for cervical cancer screening, its maker Teal Health said on Friday, offering an alternative to Pap smears that need to be undertaken at a doctor's office.
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💯
Folks, always share your code. It doesn’t have to be perfect to be helpful. And if you feel that it’s still too messy or not sufficiently clean to be shared, you shouldn’t submit yet. After all, there could be mistakes in your mess.
Important thread here. This is not a novel nor unique situation.
🚨 REPLICATION REPORT UPDATE: One year ago, a tweet by John Holbein alerted me,
@ollefolke.bsky.social, and
@jopieboy.bsky.social to a paper with a shocking result about Sweden’s law criminalizing the purchase of sex.🧵
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Thank God we have this handy review to clear up this particular controversy.
So so dumb.
The EPA plans to end the Energy Star program, which has certified energy-efficient appliances for over 30 years, as part of a major agency reorganization. This move could raise costs for consumers and undermine efforts to reduce energy use and emissions
E.P.A. Plans to Shut Down the Energy Star Program
It turns out that appointing anti-vax self-promoting grifters to critical vaccine regulatory positions is bad for business.
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The FDA's top inspections official is stepping down, amid frustration with Commissioner Makary's plans
"It's fairly basic math. We know how long inspectional activities take. If they get shorter, which inspections activities are we no longer performing?"
www.cbsnews.com/news/fda-top...
FDA's top inspector abruptly resigns
Michael Rogers had worked for the FDA for more than three decades.
The Doug Jones Map.
The 2026 senate map sucks. Don’t realize it was this bad
Counterpoint. Having numerous available paths in a Democratic leaning election is not a bad outcome.
The 2026 senate map sucks. Don’t realize it was this bad
