James Briscoe
Developmental Biologist working at the Francis Crick Institute. Neural tube, morphogens, and gene regulatory networks. Editor-in-chief, Development.
London · briscoelab.org
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- Reposted by James BriscoeIntroducing the 2025 PI Fellows of our Pathway to Independence Programme Over the next year, we will be supporting this talented group of eight postdocs, providing training, mentorship and networking opportunities as they apply for independent positions. journals.biologists.com/dev/pages/pi...
- Meet the 2025 @dev-journal.bsky.social Pathway to Independence (PI) fellows Eight developmental and stem cell biologists transitioning from postdoc to principal investigator journals.biologists.com/dev/pages/pi...
- Reposted by James BriscoeSome news! I'm officially the new Executive Editor for Development @dev-journal.bsky.social, following @katherine-brown.bsky.social's 13+ years at the journal. I'll be writing a post for @the-node.bsky.social soon about what this means for me, and for the journal, but I'm excited to get going!
- Reflections from the Human Developmental Biology Initiative's public engagement team on improving science communication while building public trust. Bridging between tissue donors and discovery research. journals.biologists.com/dev/article/...
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- Congratulations to all the newly elected members of the American Academy of Arts and Sciences Including incoming @crick.ac.uk director Edith Heard www.amacad.org/new-members-...
- Reposted by James BriscoeCongratulations to Crick group leader @jamesbriscoe.bsky.social and the @uni-of-warwick.bsky.social’s David Rand on being awarded £1.3m from the BBSRC. The pair will work on establishing a rulebook defining how cells determine their ‘type’ during development. www.crick.ac.uk/news/2025-04...
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- Very pleased to have been awarded, along with David Rand at Warwick University, this new BBSRC grant Merging dynamical systems theory with molecular biology to predict & understand the principles of cell fate decision making www.crick.ac.uk/news/2025-04...
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- Please take 5 min to give your feedback to @the-node.bsky.social Over the last 15 years it's become the go-to community blog for the dev bio and stem cell community What do you want from the Node over the next 15 years?
- As we turn 15, we want to collect feedback from you, our community, to ensure the Node is still relevant and useful. If you’ve ever visited the Node to read, write and interact with the #DevBio & #StemCell community, thank you! Please spare 5min to take our survey: www.surveymonkey.com/r/7QHYQCW
- Sad news. Benny Shilo, a pioneer in dev bio & Drosophila genetics, has died. I'll remember the infectious enthusiasm and burning curiosity he brought to every conversation I had with him.
- Always a pleasure to visit @mblscience.bsky.social Looking forward to a few days at #GERN2025 www.mbl.edu/education/ad...
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- Delighted that Iva Greenwald & Gary Stuhl have been awarded the Canada Gairdner International Awarded
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- Many congratulations to @jcornwallscoones.bsky.social on the award of a Schmidt Science Fellowship Now he just needs to find a lab to host him for his post-doc www.crick.ac.uk/news/2025-04...
- Delighted to become a council member for the BBSRC Looking forward to supporting them as they continue to push back the frontiers of bioscience www.linkedin.com/posts/uk-res...
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- Congratulations to Rory Maizels delivering the @bsdb.bsky.social Beddington Medal lecture at #Biologists100
- Always a pleasure seeing previous lab members present their own lab's work The wonderful Vanessa Ribes discussing recent work on txn regulation by Pax3/7 in neural progenitors #biologists100 www.biorxiv.org/content/10.1...
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- Peer review completed within 7 days! Paying peer reviewers! Yes, it's possible. Fast & Fair peer review by @biologyopen.bsky.social More innovation from @biologists.bsky.social Details here: www.biorxiv.org/content/10.1...
- Looking forward to #biologists100 Celebrating all the innovative ways @biologists.bsky.social have supported science over the last 100 years Here's a little example: a link to the 🌳 planted for our recent @dev-journal.bsky.social paper by Libby et al forest.biologists.com/landscape/?i...
- Many congratulations to Rory Maizels. Well deserved winner of the 2025 BSDB Beddington Medal for his PhD thesis.
- Shocked and saddened to hear Paul Kulesa has died Condolences to friends and family A big loss to dev bio
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- Provocative but important commentary from Sui Huang & co Argues we need to change the paradigm of cancer origin from a somatic mutation theory to one grounded in gene regulatory networks & tissue organisation: a system level rather purely genetic mechanism journals.plos.org/plosbiology/...
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- ICYMI: discovering design rules for cis-regulatory elements with a high-throughput screen An explainer from @jcornwallscoones.bsky.social
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- Together with fellow @biologists.bsky.social EiCs we've written about the unprecedented cuts & policy changes to research in the US We stand with our US colleagues during this challenging time Science transcends borders—setbacks in one nation affect us all journals.biologists.com/dev/article/...
- Reposted by James BriscoePlease do take a moment to read this joint editorial from @biologists.bsky.social's Editors-in-Chief. I'm feeling a bit lost in knowing how to support my friends and colleagues in the US right now. I wish there were more we could do than 'just' express our concern. If there is, please get in touch!
- Science under siege: protecting scientific progress in turbulent times journals.biologists.com/dev/article/...
- Reposted by James BriscoeScientists are facing information overload as more than a million biomedical research papers are published every year. 📚 @drbeth.bsky.social investigates why so many, the rise of preprints, what it all means for peer review and how publishing could change. www.youtube.com/watch?v=Hiri...
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- Reposted by James BriscoeBig news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n
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- Interesting idea: get the sick super-rich to pay for clinical trials Alternative idea: get the super-rich to pay tax that allows democratically accountable governments to support clinical trials (and research and healthcare and....) www.theguardian.com/news/2025/ma...
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- Our latest: uncovering hierarchical design rules for cis-regulatory elements with a high-throughput screen CRE activity follows multiplicative modular rules, tuned by spacing & positioning Enables engineering synthetic CREs for predictable tissue patterning www.biorxiv.org/content/10.1...
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- This is why UK gov needs to invest in PhD training & cut visa costs for scientists Long term economic growth depends on skilled people The UK should make the most of life sciences
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- Reposted by James BriscoeAre you a clinician looking for a fully-funded postdoctoral research opportunity? 🩺 Take a look at our postdoctoral career development fellowships for clinicians, and see how you can join our vibrant community of clinician scientists. Apply by 30 April ⤵️ www.crick.ac.uk/careers-and-...
- Reposted by James BriscoeAI-based imaging of zebrafish Position with @sergemostowylab.bsky.social @fuchtermatt.bsky.social and @jamesbriscoe.bsky.social jobs.lshtm.ac.uk/Vacancy.aspx...
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- Saddened to hear Bela Novak has died Pioneering and influential systems/quant biologist. Changed how we think about the cell cycle (amongst other things). www.merton.ox.ac.uk/news/remembe...
- Good to see this from @kichevalab.bsky.social in final journal format BMP signalling drives neural tube patterning through a temporal relay mechanism Lmx1a connects fast negative feedback and slow positive regulation www.cell.com/developmenta...
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- "Genes are... the easy part" @philipcball.bsky.social argues biologists need to embrace complexity from the start, rather than beginning with oversimplified "one gene, one trait" models +1 www.cell.com/cell-systems...
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- Do you want one of the most influential jobs in dev bio? Would you like to work with the best group of editors & publishing professionals in the business? Are you interested in leading the premier not for profit community focussed journal in the field? Come be Development's next Executive Editor
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- Our latest in @dev-journal.bsky.social: an in vivo CRISPR screening approach in chick embryos to study neural cell specification from the caudal lateral epiblast (CLE) Identifies role for super elongation complex component MLLT3 A thread... journals.biologists.com/dev/article/...
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- New work from my @crick.ac.uk colleagues in @jpvincentlab.bsky.social Brinker only present in winged insects & acts to extend the range of BMP signalling in wing discs This genetic innovation might have been crucial for wing development & insect flight evolution www.biorxiv.org/content/10.1...
- I agree with @economist.com that the "Oxbridge arc" has huge potential But realising this isn't just about planning regulations People are crucial. This means increasing, not cutting, PhD training & easing skilled worker visas www.economist.com/leaders/2025...
- Saddened to hear of John Reinitz's death Reliably contrarian and argumentative but razor sharp, original and inspirational His approach to dev bio was a decade and more ahead of the field biologicalsciences.uchicago.edu/news/john-re...
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- ICYMI: Commentary on "mechanism" in dev bio Ozpolat et al argue for diverse approaches to mechanism - from molecular to systems level journals.biologists.com/dev/article/...
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- Registration open for this year's Young Embryologist Network meeting 19 May, The Francis Crick Institute, London thenode.biologists.com/yen-2025-con...
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