CNAG
The Centro Nacional de Análisis Genómico carries out projects in genome analysis to improve people’s health and quality of life
#genomics #personalisedmedicine
- 🙌¡Salimos en @lavanguardia.com! 🪼Las medusas peine revelan el origen primitivo de la regulación genómica de los animales 📰El estudio, publicado en @Nature, indica que la capacidad de controlar genes a distancia evolucionó hace 650-700 millones de años ➡️
- ⏳7 days to #nanoporeconf! Our director, Ivo Gut, will talk about how CNAG detects full-length transcripts within individual immune cells ▶️Here’s a preview: how our team is revealing the incredible diversity within our immune system 📌May 21st, London bit.ly/4hOCD7m @nanoporetech.com #genomics
- 🇮🇹Milan, here we go! CNAG will be at #ESHG2025 — find us at booth 382! Pass by and discover how we’re advancing human genomics, hereditary cancer, and rare diseases 🗣️Want to arrange a meeting with us? Drop us a line at project.manager@cnag.eu. See you there! Organised by @eshg.bsky.social
- 🚨Job alert! 🔎We're looking for a Front-End Software Engineer ➡️Join us and contribute to key projects in cancer, rare diseases, and immunology, such as Instand-NGS4P or 3TR 🗓️Deadline: 31 May 📥Applications: www.cnag.eu/jobs/front-e... #JobAlert #FrontendEngineer #Bioinformatics #Empleo #Barcelona
- 📢New paper out in @nature.com! 🧬A genetic study reveals that the Punic civilization was the 1st truly cosmopolitan! Our Comparative Genomics Group Leader, @tmarquesbonet.bsky.social, participated in a study that analysed the genomes of Phoenician & Punic individuals www.nature.com/articles/s41...
- 📢New paper out in @nature.com! 🪼Comb jellies reveal ancient origins of animal genome regulation 🧬Researchers from @crg.eu and CNAG find that the ability to control genes across tens of thousands of DNA letters evolved 650–700 million years ago 📎 www.cnag.eu/news/comb-je... #NaturePublication
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View full thread🪼What comb jellies reveal to us is that distal regulation emerged 150M years earlier than we thought! ⭐️ Another surprising discovery is that comb jellies don’t use the protein CTCF for DNA folding but a similar protein, challenging assumptions in genomic architecture #OpenScience #LifeSciences
- ➡️ This is a groundbreaking study that reveals new insights into genomic regulation and helps us understand the principles shaping our cells today 🙌Congrats to the CNAG Structural Genomics Group: @ianakim.bsky.social (first author), @encent.bsky.social , and their leader, @mamartirenom.bsky.social
- 🔎 The authors studied genomes from ancient animal lineages—comb jellies (Mnemiopsis leidyi), placozoans, cnidarians, sponges—and single-celled relatives of animals 🔬They used a technique called Micro-C to map how DNA physically folds inside the cells of each of the 11 species #MolecularBiology
- 🔝The researchers found that distal regulation, a key evolutionary innovation, likely originated in a sea creature: the comb jelly! 🧬 This ancient animal folded its DNA in a controlled way, bringing distant DNA regions into contact and enabling complex gene regulation #Evolution #DistalRegulation
- How are genes switched on? 🦠 In the simplest organisms, genes were activated by switches nearby 🐒 Animals later evolved distal regulation—folding DNA so distant regions could switch genes on, enabling complex cells without new genes But... when did distal regulation begin? ⬇️ #GeneRegulation #CNAG
- 🚀Exciting news: @easigen-eu.bsky.social has officially launched their website! At CNAG, we are proud to coordinate this project and contribute to designing a new research infrastructure for advanced genomics technologies 📎Stay tuned here: easigen.eu #EASIGEN #ResearchInfrastructures #HorizonEU
- ⭐️Did you miss the webinar by our colleague Dr. Laura Jiménez Gracia on the FixNCut protocol? 🔬Discover a reversible tissue fixation and dissociation method for single-cell assays, ensuring RNA integrity and cellular composition ▶️https://youtu.be/uAzG-x15u08 #CNAG #Webinar #SingleCell #Genomics
- 🚀 The Hologen Symposium is here! A training week of the Doctoral Network in Hologenomics (@hologen.bsky.social) 🗣️@mamartirenom.bsky.social, Structural Genomics Group Leader at CNAG, will present the discovery of fossil chromosomes 🗓️May 6th – Copenhagen www.hologen-network.eu/hologen_symp...
- 📢#DocTIS will be at #IMMUNOLOGY2025! 🗣️Dr. Julià (@vhir.bsky.social) will present a collaborative study with CNAG & other partners: “Uncovering combination therapies for immune-mediated inflammatory diseases through systems biology analysis of longitudinal patient data" doctis.eu/doctis-resea...
- 📢New paper out in @cellpress.bsky.social! 🧬Unravelling how the genome’s 3D structure is shaped during early development A study led by the Institute of Epigenetics and Stem Cells, in collaboration with CNAG through our Structural Genomics Group Leader, @mamartirenom.bsky.social 📎 goo.su/mw1PSN
- 🐁The study explores how epigenetic factors drive the formation of nuclear architecture in mouse zygotes and 2-cell-stage embryos ➡️CNAG contributed to the computational analysis of the data, helping uncover the mechanisms behind genome organisation in the earliest stages #Epigenetics #Genomics #CNAG
- 🔝Great report in @apnews.com! 🌍Our Clinical Genomics Specialist Pedro Rodríguez is leading an international effort to advance rare disease research in Senegal 🧬He collects patient samples and sends the DNA to CNAG for sequencing — 1,300 participants involved! apnews.com/article/sene... #CNAG
- 🚨 Don't miss it! 🗓️ May 7, 09:00 🗣️Dalila Julkowska, from CNAG's Scientific Advisory Board, will participate in #iDR25, discussing support for rare disease repurposing projects ➡️More information: remedi4all.org/2025-interna... #RareDiseases #Research
- 🔝We’re starting ASPIRE, a new research project on colorectal cancer! With support from @themarkfdn.bsky.social and @contracancerinv.bsky.social 🧬We’ll apply cutting-edge single-cell genomics to track tumour evolution & uncover new therapeutic windows for advanced disease 🔗 cnag.eu/projects/asp...
- 🧬Today on #DNADay, we celebrate the code of life —and the science behind it! At CNAG, we analyse over 15,000 samples/year and support 1,100+ research projects, powered by 120+ experts and cutting-edge genomic technologies ⬇️Explore the power of DNA! #Genomics #CNAG #Sequencing #HealthcareInnovation
- 🌹Bona Diada de Sant Jordi! 📖Esperem que gaudiu molt d'aquest dia tan especial, en què els carrers s'omplen de flors i de llibres 🌟Al CNAG, aquest any estem celebrant un intercanvi de llibres entre els equips: històries que volen ser llegides. Visca la cultura! #SantJordi2025 #CienciaEsCultura
- 📺 Sortim al Telenotícies de TV3! Sabíeu que el CNAG contribuirà a crear el primer catàleg d'ADN de la població europea? 🧬 Seqüenciarem 6.000 genomes de la població espanyola 🎯 L'objectiu és obtenir el genoma de referència de les diferents poblacions europees per impulsar la medicina de precisió
- 📰¡Ayer fuimos portada del suplemento 'A tu salud' de @larazonlr.bsky.social! 🌍¿Sabías que hemos iniciado un proyecto para obtener el catálogo de ADN de la población europea? En España, somos uno de los coordinadores y nos encargaremos de secuenciar 6.000 genomas 🔗 www.larazon.es/salud/arranc...
- 📣 So excited to join the new EU Commission-funded project: B1MGplus! 🙌 We are one of 36 partners supporting 1+MG and helping to create a European cross-border network of genomic and clinical data to improve healthcare outcomes 📎 More info: www.cnag.eu/projects/bey... #genomics #EU #CNAG #research
- 🚀New project for #biodiversity! 🐌CNAG will generate the genomes of endangered molluscs in Catalonia, under the umbrella of the @catbiogenoma.bsky.social and funded by the @iec.cat 🧬We’ll carry out the entire process, from sequencing to chromosome-level assemblies 📎 www.cnag.eu/projects/bui...
- 🔬Saps quins són els hubs i initiatives científiques a Catalunya en l'àmbit de les ciències de la vida i la salut? Aquí teniu el mapa amb les 50 infraestructures que impulsem la innovació per la salut de les persones. 🌍Som referents a Europa! ➡️@biocat.cat: www.biocat.cat/ca/sala-de-p...
- 📚Fem divulgació de la genòmica! 👩🔬La nostra investigadora del CNAG, la Dr. Laura Jiménez, va fer una xerrada i un taller als estudiants de 4rt de la ESO i batxillerat d'un institut de Maó sobre CRISPR, single-cell genomics i les dones a la ciència ➡️Programa #AmgenTransferCiència (FCRI i Amgen)
- 🐺Heu sentit que la biotecnològica Colossal Biosciences ha 'ressuscitat' al llop gegant, extingit fa més de 10.000 anys? 📺El Dr. @mamartirenom.bsky.social, investigador del #CNAG, us ho explica en aquest reportatge de TV3 🚨Spoiler: no és una 'desextinció'! 🔗 www.3cat.cat/324/llums-i-... #Genetica
- 🌎Ahir, vam participar en una jornada amb universitats dels EUA organitzada per la @fundaciorecerca.bsky.social 👩🔬La nostra Dr. Laura Jiménez Gracia va presentar el programa AmgenTransferCiència, destinat a fomentar la vocació sobre genètica i biotecnologia entre els alumnes d'ESO i batxillerat #CNAG
- 🌟Big step in #PrecisionMedicine: CNAG publishes an inflammation atlas with 6.5 million single cells from 1,047 patients across 19 diseases! 🎯Key to understanding inflammation in infections, autoimmune diseases & cancer Led by @hoheyn.bsky.social, under Doctis Proj. www.biorxiv.org/content/10.1...
- 🌟New reference genome for the @ergabiodiv.bsky.social! 🐍This time, we dive into the evolutionary secrets of the Western Montpellier snake's venom 🧬CNAG extracted the DNA, prepared the libraries, and carried out sequencing, genome assembly and curation ➡️ biodiversitygenomics.eu/2025/04/09/u...
- 📢Hoy, nuestro experto en start-ups de CNAG, @albert-domingo.bsky.social, participará en la mesa redonda sobre emprendimiento y ecosistemas de innovación de las jornadas #INNOLABLOGÍSTICA, organizada por CEL Logística 🗓️13.10h 📍Dfactory Barcelona ➡️Más info: cel-logistica.org/curso/8-abri...
- 🗣️Hace unos días, nuestro director Ivo Gut asistía al lanzamiento de un nuevo secuenciador de nueva generación, AVITI (de Werfen y Element Biosciences) 🧬Durante el evento, participó en una conferencia y en una mesa redonda sobre últimas tendencias en tecnologías de nueva secuenciación #CNAG #NGS
- 🏆Big news: Dr. Sergi Beltran, Head of our Bioinformatics Unit at CNAG, has received the 2025 Chen Award of Excellence from @humangenomeorg.bsky.social for his exceptional contributions to bioinformatics and human genetics! 🔗 www.cnag.eu/news/sergi-b... #ChenAward #Genomics #RareDiseases #GPAP
- 🚀New research published in @naturecomms.bsky.social! 👉'Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 overcomes macrophage immunosuppression in cancer', with @paulanietog.bsky.social and @hoheyn.bsky.social from CNAG 📎 www.nature.com/articles/s41...
- 🔬The new publication is a major step in uveal melanoma research! ➡️The study shows that the experimental treatment tebentafusp reshapes the tumor microenvironment to boost T cell activity. Combining it with IL-2 may further benefit patients with high tumor-associated macrophages #Immunotherapy #CNAG
- 📢New paper out in Oncogene! ➡️'Transcriptional reprogramming triggered by neonatal UV radiation or Lkb1 loss prevents BRAFV600E-induced growth arrest in melanocytes', with the collaboration of @paulanietog.bsky.social, Ginevra Caratù and @hoheyn.bsky.social (CNAG) 📎 www.nature.com/articles/s41...
- 🧬Our Single Cell Genomics Group contributed to this study, led by @vhio.bsky.social, which reveals that BRAFV600E-mutated melanomas can develop independently of nevus progression 👉This insight opens the door to new therapeutic targets for melanoma treatment #Melanoma #Research #Cancer #Genomics
- 🎉A few days ago, we wrapped up the first Bridging-RD training! 🔬Dr. Steve Laurie (Human Genetics team) shared key insights with PhD students from @IMGGE, helping them enhance their skills in bioinformatics tools to improve #RareDiseases diagnosis 🔗More information: cnag.eu/projects/bri...
- 📢New job opportunities at CNAG! 🔎Explore our latest openings and join an international centre for genomic analysis: ▪️ Junior People Assistant ▪️ 3 PhD candidates – STEP Technologies (FI-STEP) ▪️ PhD Student – Structural Genomics Group 📥Apply here: cnag.eu/jobs #JobOffer #WeAreHiring #Barcelona #Jobs
- 🚀Excited to share our 2024 Annual Report! 🔝A summary of the key milestones we hit last year, from expanding sequencing capacity to strengthening our role in clinical genomics. 🙌Thanks to all our partners, especially our teams, for making it possible! 📎https://goo.su/CVNR #CNAG #AnnualReport #ICTS
- 🌍¡Arranca Genome of Europe! 🎯Su objetivo: secuenciar 100.000 genomas de las poblaciones europeas, para ayudar a la medicina personalizada en cáncer y enfermedades raras ➡️CNAG es coordinador de los centros de secuenciación, y generará 6.000 genomas www.lavanguardia.com/sociedad/202...
- 🙌¡Hoy hemos recibido la visita de nuestro Consejo Rector! 👥Nos han acompañado los representantes del Ministerio de Ciencia, Innovación y Universidades y de la Generalitat de Catalunya 🧬Una jornada muy completa, en la que han conocido la Sala de Secuenciación y el Centro de Procesamiento de Datos
- 👏Molt orgullosos de formar part d'aquesta iniciativa per la biodiversitat! 🦋Al CNAG, ens dediquem a seqüenciar les mostres d'espècies endèmiques del territori de parla catalana, per després obtenir el seu genoma de referència que ajudarà a la seva qualitat de vida i supervivència Més informació ⬇️
- 🚀Don't miss out! 📅Today at 5 PM – New webinar: "STAMP: Single-Cell Transcriptomics Analysis and Multimodal Profiling through Imaging" 🎙️With Emanuele Pitino and @pascual-reguant.bsky.social Pascual (CNAG), by @brukerspatial.bsky.social 🔗https://go.brukerspatialbiology.com/CosMx-STAMP-webinar.html
- 🚨 Join Our Team at CNAG! If you’re passionate about genomics and want to work in a dynamic, cutting-edge environment, check out our latest job opportunities: ➡️1 Junior People Assistant ➡️3 PhD candidates - STEP technologies (FI-STEP) 🔗Apply here: cnag.eu/jobs #Hiring #Genomics #JobOpportunity
- 🙌 Exciting news! Our article in Molecular Ecology Resources is in the top 10 most-cited papers! Big congrats to Marta Gut, Head of the Sequencing Unit at CNAG, and Tyler Alioto team! 📎https://onlinelibrary.wiley.com/doi/full/10.1111/1755-0998.13750 #TopCitedArticle #Research #CNAG #Biodiversity
- 🔎 Discover the latest advances in treatments for Immune-Mediated Inflammatory Diseases in the #DocTISProject #webinar 🗣️ Featuring @hoheyn.bsky.social, our Single Cell Genomics Group Leader, discussing molecular data generation from IMID Biobank patients 🔗 doctis.eu/relive-docti... #IMID #CNAG
- 🚀New advances in Screen4Care! At CNAG, we’ve begun processing the first samples, which have already been sequenced 🎯The project aims to accelerate rare disease diagnosis through genetic screening and advanced analysis in newborns www.cnag.eu/news/new-eu-... #RareDiseases #Genomics #Bioinformatics
