Max Perutz Labs Vienna
The Max Perutz Labs are a joint venture of @univienna.bsky.social and the Medical University of Vienna, dedicated to a mechanistic understanding of fundamental biomedical processes.
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- 🚨 New publication! RAF1, known for its role in the MAPK pathway, now has a surprising new function. In a @cp-cellreports.bsky.social study, Stefanie Toifl (Baccarini lab) reveals that RAF1 is essential for autophagic lysosome reformation ➡️ tinyurl.com/4tw2twn5 @univie.ac.at @meduniwien.ac.at
- Edvinas is this month's Researcher of the Month! 🤩🙌
- 💯🔬Fascination #cells: Edvinas Stankunas from @maxperutzlabs.bsky.social & #MedUniVienna is researching a central building block of the #nuclearpore. Aim: to reconstruct the complex in the laboratory in order to better understand malfunctions and disease mechanisms. ➡️ bit.ly/3YyiJa6
- 🏆 Congrats to PhD student Edvinas Stankunas, who has been named Researchers of the Month from the Medical University of Vienna 👏 Edvinas is featured for his publication in Nature Cell Biology in 2024 - a well-deserved recognition! Watch here ➡️ tinyurl.com/dhpamekv @univie.ac.at @meduniwien.ac.at
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- 📑 New study! Why would cells invest in a protein that degrades within minutes? TRIM52 is one of the most unstable proteins in the human proteome. Research by @versteegga.bsky.social in Nature Communications reveals its advantageous role ➡️ tinyurl.com/yw6wtzkc @univie.ac.at @meduniwien.ac.at
- Sowmya Geetha (Jantsch lab) defended her thesis "Bloom helicase contributes to successful crossover formation with both catalytic and structural roles in C. elegans meiosis" 🪱 - congratulations! 👏 @univie.ac.at #phdone
- 🏛️ The institute building has developed, just like the science inside it. Over the past 20 years, the home of the Max Perutz Labs has evolved into a modern place shaped by curiosity, collaboration, and innovation 🙌 Swipe through two decades of transformation! #MaxPerutzLabs20Years
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- Big congrats to postdoc Virginia Busetto from the Falk lab on receiving the prestigious ESPRIT fellowship from the @fwf-at.bsky.social! 🪱 Her project explores how the RNA endoribonuclease RDE-8 is precisely regulated to protect genome stability - well deserved! ➡️ tinyurl.com/bdeppsyj @univie.ac.at
- Welcome to the Perutz, Felix! 🙌
- Welcome to the Perutz, Siwen! 👏
- 🚨 Out now! The Leonard lab reveals in @pnas.org that phosphatases PHLPP1/2, once thought to dephosphorylate Akt and suppress tumors, are actually catalytically inactive. Instead, they have a non-catalytic role, reshaping our understanding of Akt regulation ➡️ tinyurl.com/hf28b3mu @univie.ac.at
- 🎉 Today, we look back on a milestone moment in Perutz history! On this day in 2005, the rectors of the University of Vienna and the Medical University of Vienna, Georg Winckler and Wolfgang Schütz, signed the notarial deed, officially establishing the Max Perutz Labs. 🧬🎊 #MaxPerutzLabs20Years
- 🎓 Congratulations to Helena Bragulat Teixidor from the @labotsuka.bsky.social on successfully defending her thesis "Revealing the functional ultrastructure of the junctions connecting the endoplasmic reticulum to the nuclear envelope using three-dimensional electron microscopy"! 🔬 @univie.ac.at
- Congrats to Nobel Laureate and former Perutz faculty member Emmanuelle Charpentier on receiving an honorary doctorate from the @univie.ac.at! 🎉 Last week, she returned to the @vbcscitraining.bsky.social for an inspiring Public Lecture ➡️ tinyurl.com/yu3tvyxa (c) Joseph Krpelan
- Welcome to the Perutz, Felix! 🤩
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- 🆕 New publication! The nuclear periphery usually contains inactive genes, but some active ones are also present. What keeps them there? 👀 A study from the Foisner lab in Nature Communications reveals a novel tethering mechanism. ➡️ tinyurl.com/mr49wmdb @univie.ac.at
- 👏 Congrats to Sarah Schweighofer, postdoc with @jonasries.bsky.social, on being awarded a Marie Curie fellowship! She will explore how mitochondrial fragmentation is regulated during programmed cell death using super-resolution microscopy 🔬✨ Read more ➡️ tinyurl.com/2p8yacme @univie.ac.at
- Welcome to the Perutz, Sascha! ☺️
- Welcome to the Perutz, Jovana! 🙌
- 🎉 Congratulations, Harald Hornegger from the Karagöz lab! Harald successfully defended his thesis "Phosphorylation of disordered regions regulates the function of the RNA-binding protein IGF2BP1" - #phdone 🙌🎓 @univie.ac.at
- 🇯🇵 Congratulations to @shotarootsuka.bsky.social on receiving the Kazato Prize! 🏆 This award honors outstanding young Japanese researchers making significant contributions to electron microscopy research and development 👏🔬 Omedetō, Shotaro! @univie.ac.at
- Welcome to the Perutz, Carla! 🤩
- 💻🔧 Join our team! The Perutz is looking for a reliable, team-oriented IT support specialist with a passion for solving IT challenges. As the first point of contact for support requests, you'll handle hardware, software, and network issues. More (in German) ➡️ tinyurl.com/mve22zuu
- 🎉 Perutz group leader and @embl.org alumna Irma Querques received the John Kendrew Award for her groundbreaking research in genome editing 🏆 Named after John Kendrew, who won the 1962 Nobel prize in chemistry alongside Max Perutz, this award carries a special significance ➡️ tinyurl.com/4ep7vzhb
- 🤔 Ever wondered how top-quality monoclonal antibodies are made? In the fourth part of our facilities series, we take you inside the Monoclonal Antibody facility, where experts produce tailor-made antibodies ➡️ tinyurl.com/mt29aac5 @univie.ac.at
- Another tenured professor at the Perutz - congrats to @sebastianfalk.bsky.social! 👏 His lab, established in 2019, explores how small RNAs control gene expression through the RNA interference pathway 🔎 More ➡️ tinyurl.com/4c86dmr5 @univie.ac.at
- You are passionate about mobile DNA, structural biology, and genome engineering? 👀 Exciting #postdoc opportunity ahead! @irmaquerques.bsky.social's lab is seeking a postdoctoral researcher with a background in biochemistry and structural biology (cryo-EM) 🥼 More ➡️ tinyurl.com/nd9zbmt6
- 💻 Are you an IT enthusiast and problem solver who enjoys tackling tech challenges and helping people? Then this opportunity is for you! The Max Perutz Labs are looking for an IT support allrounder to maintain IT services and provide first-level support. More (in German) ➡️ tinyurl.com/y46uderk
- ❕Master's thesis opportunity! The Martens lab is offering a Master's project to investigate how Parkinson's disease aggregates impact the human brain 🧠 Don't miss this chance to dive into cutting-edge research ➡️ tinyurl.com/22epxz4r
- Long before the Max Perutz Labs were officially founded in 2005, a group of ambitious young molecular biologists - some of them shown below - dreamed of creating a research institute that would unite the strengths of scientists in a cross-university initiative 🙌 #MaxPerutzLabs20Years @univie.ac.at
- 👩🎓 Paulina Kettel (Karagöz lab) defended her thesis titled "Deciphering the early activation mechanisms of the unfolded protein response by proteotoxic endoplasmic reticulum stress" and earned her hat! Congrats, Paulina 🤩🎉 @univie.ac.at
- 👏 Congrats to Irene Schwartz from the Versteeg lab on completing her PhD with her project "Protection from endogenous cancer-associated APOBEC3 deaminases through proteasomal degradation"! 🙌 #phdone @univie.ac.at
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- 📑 New study out now! The Kovarik lab uncovers a novel mechanism for eliminating pro-inflammatory pre-mRNAs in the nucleus - preventing the overproduction of cytokines published in Molecular Cell ➡️ tinyurl.com/m8p87k6k @univie.ac.at
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- Congrats to Perutz group leaders Elif Karagöz and @shotarootsuka.bsky.social on becoming tenured professors 🎉 Since 2019, the Karagöz lab has been uncovering how cells maintain protein homeostasis, while the Otsuka lab explores how the ER and nucleus communicate ➡️ tinyurl.com/2phzhprj
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- Paper alert! 📢 RNA-protein interactions are well-documented, but their relationship with biological coding has remained elusive - until now 🔎 In @pnas.org, the Žagrović lab uncovered specific examples of RNA-protein interactions embedded within the genetic code ➡️ tinyurl.com/3t33hrzm @univie.ac.at
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- 🎉 Congratulations to @jonasries.bsky.social on receiving an ERC Proof of Concept grant! With his project 'PhaseFLUX', Jonas is working on a microscope prototype to enhance the MINFLUX technology 🔬 #ERCPoC ➡️ tinyurl.com/yc4yww3k
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- 🎉 Congrats to @marcoyannic.bsky.social on securing a WWTF grant! Partnering with Irene Görzer from the Medical University of Vienna, Marco will delve into the largely unexplored world of anelloviruses - ubiquitous, commensal members of the human virome 🦠 Read more ➡️ tinyurl.com/yk5zfcmh
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- 🫵 You are interested in recombinant protein purification, quantitative biochemistry and structural biology? Great Master's project ahead! 🤩 The Leonard lab offers a project to elucidate the mechanism(s) by which the ISR kinases specifically recruit eIF2 📶 Read more ➡️ tinyurl.com/238r7rkb
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- 2025 marks an incredible milestone: it is the 20th anniversary of the Max Perutz Labs! 🎉 This is a chance not only to celebrate how far we’ve come but also to be inspired by the bold vision that started it all and to carry that energy forward into the next 20 years. Stay tuned! #MaxPerutzLabs20Years
- 🚨 Out now! @marcoyannic.bsky.social and his former colleagues at the Chan Zuckerberg Biohub have unveiled a new study in Cell. The team led by Manuel Leonetti mapped the subcellular distribution of thousands of proteins to create an atlas of the human proteome ➡️ tinyurl.com/ypn65duk @univie.ac.at
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- The Max Perutz Labs wishes everyone a relaxing holiday season filled with joy and a 2025 filled with success, new ideas, and groundbreaking science! 🎄🎁🌟 Stay curious, stay inspired, and see you in the new year! 🎊
- 🔬 Microscopes are a cornerstone of any life science lab - and at the Perutz, the BioOptics Light Microscopy and Histology facilities have you covered! ✨ In the third part of our Perutz facilities series, we spotlight these two essential hubs 🧫🧠 Watch their video here ➡️ tinyurl.com/2jyr3cer
- 👀 Exciting Master's project in the Karagöz lab open! The team explores how cells respond to proteotoxic stress and is now diving into a new project to uncover how ER chaperones regulate the unfolded protein response (UPR) 💡 Don't miss the chance ➡️ tinyurl.com/3wjedm5b
- Master's thesis opportunity❕ The Bachmair lab offers a project about the biochemical and cell biological analysis of protein turnover driven by amino-terminal degradation signals in plants 🌱 More information ➡️ tinyurl.com/bddmb97y
- ✨ Are you creative, critical, and communicative? Passionate about science and ready to make an impact? 💪 The Querques lab is looking for a research technician! Apply here ➡️ tinyurl.com/ak8b5zhw
- Great news from the Slade lab! Postdoc Lisa Appel and PhD student Johannes Benedum have been named Researchers of the Month from the Medical University of Vienna, celebrating their outstanding publications in Nature Communcations last year 🏆👏 ➡️ tinyurl.com/42kybvsb
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- Paper alert! 📢 The inner nuclear membrane is a hub for the lipid metabolism. In a new @natureportfolio.bsky.social Comms study, the Köhler lab uncovers Seipin as a key regulator in maintaining lipid balance and nuclear envelope integrity 🌟 Read more ➡️ tinyurl.com/ycy7pjkh @univie.ac.at
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- 👏 Big congrats to Perutz group leader Christa Bücker @chribue.bsky.social on receiving the prestigious ERC Consolidator Grant! With GENE-TUNE, the Buecker lab will take a bottom-up approach to decode the complexities of gene regulatory landscapes ➡️ tinyurl.com/ybhucz3u #ERCCoG @univie.ac.at
