Marco Trizzino
Associate Professor of Developmental and Evolutionary Genomics at Imperial College London, Department of Life Sciences. Spent a decade in Philly, #FlyEaglesFly
marcotrizzino.wordpress.com
- Reposted by Marco Trizzino“Poor man wanna be rich. Rich man wanna be king. The king ain’t satisfied ‘til he rules everything.”—Springsteen, Badlands
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- Reposted by Marco TrizzinoThrilled to share our latest study out in @natureportfolio.nature.com led by the fantastically talented Jing Liu. Our study provides insight into a long standing question in biology: What molecular features make us uniquely human and how do these function? www.nature.com/articles/s41...
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- Reposted by Marco TrizzinoOn this day May 13th, 1985 the city of Philadelphia dropped a bomb on the Move Home at 6221 Osage Avenue killing 11 people including 5 children. collaborativehistory.gse.upenn.edu/stories/move...
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- Reposted by Marco TrizzinoNew notice on NIH foreign awards Perhaps some useful clarity and information grants.nih.gov/news-events/...
- And just like that, overnight our lab loses two 5-year R01s (both of which just started) because of the new NIH rules about foreign co-PIs. This is so painful.
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- Reposted by Marco TrizzinoRemember when you first learned about genetics at school? All those fascinating examples of human traits that are each apparently determined by just a single gene? Time to check in on some of your favourites to see how they’re doing. 🧬🧵🧪 1/n
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- Masterpiece!
- So the way I read the guidance, foreign institutions would still be allowed as long as they are directly awarded and not subwarded? grants.nih.gov/grants/guide....
- Reposted by Marco TrizzinoNIH announced it will no longer allow subawards to foreign institutions, as part of a national security-minded overhaul to how it manages research funding
- Reposted by Marco TrizzinoRFK Jr: "We found that there's a direct inverse correlation between fluoride exposure and low IQ in children. So the more you get, the stupider you are."
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- Reposted by Marco TrizzinoNIH has cancelled its participation in Safe to Sleep, a 30-year campaign to prevent babies from dying in their sleep www.statnews.com/2025/04/30/n...
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- Reposted by Marco TrizzinoCheck out our latest preprint, led by Dr. Siyu Chen, that brings together an amazing team of scientists from several labs ( @vram142.bsky.social, Tavazoie, and Navickas) to tackle a fundamental problem in biology: how do cells regulate expression of their tRNAs? www.biorxiv.org/content/10.1...
- Reposted by Marco Trizzino💥🥳 At long last, our latest paper is out! Gag proteins of endogenous retroviruses are required for zebrafish development www.pnas.org/doi/10.1073/... Led heroically by Sylvia Chang & @jonowells.bsky.social A study which has changed the way I think of #transposons! No less! 🧵 1/n
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- Reposted by Marco TrizzinoIf you're a new PI within 5 years of your first faculty position, here are two fantastic grants to help develop your research: the Kickstart Travel Grant & ECR Visiting Fellowships Find out more at biologists.com/grants/#jeb The next application deadline is 6 June Please repost to spread the word
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- Reposted by Marco TrizzinoWe released our preprint on the CREsted package. CREsted allows for complete modeling of cell type-specific enhancer codes from scATAC-seq data. We demonstrate CREsted’s robust functionality in various species and tissues, and in vivo validate our findings: www.biorxiv.org/content/10.1...
- Reposted by Marco TrizzinoThe rest of Mendel's alleles characterized! So, out of 7 traits, 3 caused by TE insertions!!! (though apparently there are two different green alleles, one cause by a TE insertion, but another a promoter deletion allele) www.nature.com/articles/s41...
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- Reposted by Marco TrizzinoIn what proportions is our new NIH Director a flaming ignoramus vs. a brazen liar?
- Reposted by Marco TrizzinoWell the NIH has cancelled the Women's Health Initiative, the largest study of women in history It has been running continuously since 1991 and has provided massive key knowledge about diseases in women Unreal www.science.org/content/arti...
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- This will be a game changer!
- Silencing of transgenes during iPSC differentiation is a frequent problem. 🧬🫢 Check out the piggyBac system below, which has resisted silencing in many protocols across many labs. 💪 Excited that our lab could contribute to this team effort led by @tuenaka.bsky.social & Marius Wernig!
- Reposted by Marco TrizzinoMore from the Washington Post (and this one is a doozy) regarding the President's Budget. Note that this is an aspirational document and Congress has to act (or ignore it). [Gift Link] wapo.st/42gLz0Z 1/n
- Reposted by Marco TrizzinoLosing sleep over #iPSC transgene silencing after differentiation? Same here — too many times😭 So we built a PiggyBac construct that resists silencing. Expression stays ON, even after differentiation. Our #preprint is out👇 🔗 www.biorxiv.org/content/10.1... Supported by @cziscience.bsky.social
