Journal of Clinical Neuroscience
The official journal of the Neurosurgical Society of Australasia, the Australian and New Zealand Society for Neuropathology, the Taiwan Neurosurgical Society, and the Asian Australasian Society of Neurological Surgeons
- 🧠✨ Hot off the press! The June issue of JoCN is packed with the latest insights! 🔍 Cutting-edge reviews on brain AVMs, the gut-brain axis in TBI, glioma, MS, spine surgery & more! 📚 sciencedirect.com/journal/jour... #Neurosurgery #NeurocriticalCare #TBI #Neuroimaging
- Can a liver fibrosis score predict stroke outcomes? High FIB-4 scores (>2.67) were linked to worse 3-month outcomes and higher mortality in IV tPA-treated stroke patients. www.sciencedirect.com/science/arti... #Stroke #LiverFunction #tPA #NeuroTwitter #MedTwitter
- Why do some patients with refractory status epilepticus not make it out of the hospital? New data highlight key risk factors: • Hemodynamic instability • Seizure recurrence • Older age Surprise: prior epilepsy = lower mortality www.sciencedirect.com/science/arti... #Epilepsy #NeuroICU
- ⛔️⚠️Post-op pneumocephalus in chronic subdural hematoma isn’t just air—it’s a risk. This meta-analysis of 3,200+ patients finds massive pneumocephalus triples recurrence risk and worsens prognosis. No mortality difference, but outcomes matter. #Neurosurgery www.sciencedirect.com/science/arti...
- 🧠🩸Over 20 years, non-traumatic ICH mortality is down—but hospital stays are up and rural-urban gaps persist. Complexity climbs, outcomes improve, equity lags. www.sciencedirect.com/science/arti... #Stroke #NeuroICU #HealthEquity #ICH #NeuroTwitter #MedTwitter #CriticalCare
- TBI meets the Gut-Brain Axis. Disruptions in gut microbiota post-TBI can fuel chronic neuroinflammation, cog decline, and poor recovery. Can probiotics, SCFAs & precision diets be the future of TBI care? www.science direct.com/science/article/pii/S0967586825002309 #TBI #NeuroRecovery
- 🧠 Carotid webs: a hidden threat in young stroke patients. Review of 788 cases reveals high recurrence with medical management alone—but zero recurrence with stenting or endarterectomy. 🔗 doi.org/10.1016/j.jo... #Stroke #CarotidWeb #Endovascular #Neurosurgery
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- 🌟🧠National analysis reveals high-risk factors for poor outcomes after cerebral cavernous malformation (CCM) resection—especially acute bleeding, non-elective admissions, and socioeconomic disparities. Read more: doi.org/10.1016/j.jo... #Neurosurgery #HealthEquity #Neurovascular #MedTwitter
- New data from a 12.5-year single-center review of endovascular tx for post-hemorrhagic cerebral vsp (PHCV): • 41% achieved good outcomes (mRS ≤ 2) • 200 procedures in 82 patients • Comp rate ~5% • GCS predicted outcomes doi.org/10.1016/j.jo... #Neuro #NeuroIR #SAH #NeuroCriticalCare
- New study identifies risk & protective factors for late-onset MS (LOMS): ☀️Sunlight exposure in adolescence & adulthood is protective 😩Stress, depression, intense physical activity, & family hx of MS increase risk Full article: doi.org/10.1016/j.jo... #MultipleSclerosis #NeuroEpi #neurology #Neuro
- New systematic review finds mask-based Gamma Knife SRS offers comparable tumor control and safety to frame-based SRS for brain metastases—enhancing patient comfort. Read more: www.sciencedirect.com/science/arti... #SRS #RadOnc #Neurosurgery
- Cementing better outcomes: Bone cement cranioplasty (CCP) lowers CSF leaks, infections, and reoperations after retrosigmoid CPA surgery. Meta-analysis supports CCP over non-cement reconstruction. Read here: doi.org/10.1016/j.jo... #Neurosurgery #Surgery #neurology #surgicaltechniques
- Can SRS help in recurrent high-grade gliomas? In this study, SRS achieved 70% local control at 3 months, with MGMT methylation linked to better survival. More insights here: doi.org/10.1016/j.jo... #NeuroOncology #Glioma #RadOnc
- New meta-analysis finds MR-guided focused ultrasound (MRgFUS) has a favorable safety profile for treating medication-refractory #ParkinsonsDisease. Most common adverse event? Dizziness. No sig ⬆️ in life-threatening events. doi.org/10.1016/j.jo... #FocusedUltrasound #Parkinsons #Neurology
- 👀Nice case of cavernous sinus syndrome: 36-year-old male with ptosis, ophthalmoplegia caused by a pituitary tumor extending into the cavernous sinus. Read more: doi.org/10.1016/j.jo... #NeuroTwitter #Neurology #Neurosurgery #CavernousSinus #CranialNerve #NeuroOphthalmology #PituitaryTumor
- 🚨 Unplanned extubations in the NeuroICU = preventable risk. A multidisciplinary, unit-based practice ⬇️unplanned extubations from 0.93 to 0.22 per 100 ventilator days at an academic center. 📄 www.sciencedirect.com/science/arti... #NeuroICU #PatientSafety #QI #CriticalCare #HRO #ICUcare
- 🚨AI meets epilepsy care: machine learning algorithm + large language model helped ID candidates for epilepsy surg referral with promising accuracy. Streamline reviews & boost timely referrals. 🧠💻 #NeuroAI #Epilepsy #DigitalHealth 🔗https://www.sciencedirect.com/science/article/pii/S096758682500116X
- May 2025 issue of JoCN: 🩸 Neurovascular Innovations 👩💻 Neurotechnology Frontiers 🧠 Global Neurosurgery Access 💡 Neurorehabilitation Strategies www.sciencedirect.com/journal/jour... #Neuroscience #Neurotech #StrokeCare #ParkinsonsResearch #Neurosurgery
- 🎥 Complex clival chordoma? Watch a combined endonasal + endo-oral approach with maximal safe resx of a tumor. Meticulous flap work + panoramic skull base access = surgical success. 🔗https://www.sciencedirect.com/science/article/pii/S0967586825000979 #Neurosurgery #SkullBaseSurgery #ENT
- 🚨 New Meta-Analysis 🚨 Does pre-op embolization improve AVM microsurgery outcomes? 🧠 43 studies, 3916 patients 🟰 No significant differences in: fx dep, bleeding/blood loss 📊 Stratified by Spetzler-Martin grade More data needed for SM III AVMs. 🔗 doi.org/10.1016/j.jo... #Neurosurgery #AVMs#NeuroIR
- 📊 In #ChronicSubduralHematoma, hematoma volume (HV) predicts motor symptoms & recurrence. Midline shift (MLS) links to consciousness disturbance. RCAI-CR highlights brain compression. New data to guide surgical risk stratification & follow-up. 🔗 doi.org/10.1016/j.jocn… #Neurosurgery #NeuroRad
- New study highlights key age-related differences in #NMOSD outcomes. Patients with late-onset NMOSD had poorer functional prognosis, especially if AQP4-ab(+). Read more: www.sciencedirect.com/science/arti... #Neuroimmunology #MultipleSclerosis #DemyelinatingDiseases #NeurologyResearch
- 🧠🧐Exploring progress in neuromodulation for stroke treatment! Abraham et al. review 996 clinical trials, highlighting tDCS & TMS for motor recovery. Read more: doi.org/10.1016/j.jo... #Neuromodulation #Stroke #Neurosurgery #strokerecovery #vascularneurology
- Neurosurgical boot camps are an effective strategy to improve medical student preparedness for sub-internships💪💪 #meded #neurosurgery #simulation #medtwitter @SalahGAoun et al. doi.org/10.1016/j.jo...
- Who does it better when it comes to writing scientific articles? AI vs. humans? doi.org/10.1016/j.jo... #neurosurgery #neurology #meded #AImedicine #artificalintelligence
- 🧠Teaching neuroimage: PML presenting as tumefactive demyelination in an immunocompetent person #neurology #neuroID #radiology #neuroradiology doi.org/10.1016/j.jo...
- How would you manage a penetrating pencil injury to the eye? doi.org/10.1016/j.jo... #neurosurgery #trauma #TBI
- 🧠⚠️ Laughing gas, serious consequences: 'whippets' can lead to B12 deficiency, SCD and an 'inverted V' sign on MRI. doi.org/10.1016/j.jo... #SpineHealth #SubacuteDegeneration #neurology #brainhealth
- 🧠🧐You’ve heard of trigeminal neuralgia but have you heard of nervus intermedius neuralgia?! pubmed.ncbi.nlm.nih.gov/38308978/ #neurosurgery #neuralgia #neurology #RareDiseases
- 🔍Discover the artery of Wollschlaeger & Wollschlaeger (AWW) – a tiny marvel with a big impact in neurosurgery. Dive into its anatomy, significance, and clinical role in this fascinating review! #neuroscience #neurology #neurosurgery #medicalhistory doi.org/10.1016/j.jo...
- Transcranial Doppler (TCD) shows elevated blood flow velocities persist beyond 90 days in 81% of RCVS patients. TCD may aid diagnosis when CTA/MRA miss vasospasm. More research needed on duration & treatment. #neurology #stroke #brainhealth #ultrasound doi.org/10.1016/j.jo...
- New meta-analysis: TXA associated with less 🩸rebleeding in aSAH (RR 0.61, P<0.00001) but not improvement in survival, DCI or outcomes. Full study: doi.org/10.1016/j.jo... #neurosurgery #TXA #aSAH #stroke #neurocriticalcare
- 🧐🧠🩸Cerebral vasospasm post TBI is associated with more severe TBI and longer ICU stays. Could detection represent a potential intervention point? Ernst et al. doi.org/10.1016/j.jo... #TraumaticBrainInjury #Vasospasm #Neuroscience #Neurology #stroke #brainhealth
- 🧠🫁Hyperoxia in non-traumatic SAH? Worse outcomes and more DCI. Let’s rethink oxygen—are more trials needed? #SAH #HyperoxiaHurts #BrainHealth #NeuroICU #Neurology Catalano et al. doi.org/10.1016/j.jo...
- 🧠👀Seeing concussions in a new light: Quantitative pupillometry could revolutionize diagnosis with objective precision. Bashir et al. pubmed.ncbi.nlm.nih.gov/39724819/
- 🧠Dr. Juhn Wada (1924-2023) revolutionized #neurology care with the Wada test. He used sodium amytal injections to map brain functions like language & memory before surgery, improving patient outcomes. A true pioneer in #neurosurgery! #WadaTest #Epilepsy Li et al. pay tribute: lnkd.in/gUCR8wKh
- 🧠Brainstem surgery sounds ominous, right? But what if 'safe zones' could make it less risky? A study by Edelbach et al. tackles pontine brainstem cavernomas with precision Check it ➡️ doi.org/10.1016/j.jo... MRI from Kar et al., link.springer.com/article/10.1... #neurosurgery #neurology #stroke
- Melanoma masquerading as meningioma: A rare intracranial case unveiled during surgery on a 31yo male. #Neuroscience #BrainTumor #Neurosurgery doi.org/10.1016/j.jo...
- Happy #Match2025!! Excited to see past and future authors matching into their chosen specialities. Special affinity for #neurology #neurosurgery #radiology but much love to all!
- Blossoming brain aneurysm treatment: The 'flower bud & push' Woven EndoBridge technique - safe, versatile, and blooming with potential! #MedTech #Neurosurgery #neurology #neurovascular Tanabe et al. doi.org/10.1016/j.jo...
- From vision changes to victory: a phosphaturic mesenchymal tumor in the brainstem was behind a patient’s woes. Post-resection, his phosphate levels normalized. Ever seen a case like this? Share your thoughts! #Neurology #RareDisease #Neurosurgery Wu et al. www.sciencedirect.com/science/arti...
- Wernicke’s doesn’t just happen in alcoholics—patient post-gastrectomy with deadly repercussions from thiamine deficiency. Would prophylaxis with thiamine help? Yuzkan et al. doi.org/10.1016/j.jo... #neurology #medtwitter #FOAM #neuroscience #brainhealth #brain #neurotwitter #neuroradiology
- ❓Immunocompetent patient living in Brazil presents with headache, vomiting and cough. Imaging 🔻🔻 Differential diagnosis? 🧠🫁comment before looking at the link! Correa et al. doi.org/10.1016/j.jocn… #neurology #neurorad #infectiousdisease #brain #brainhealth
- 🧠Which is better for #neuroendovascular procedures: transradial 🆚 transfemoral access? Elfil et al. explore access for MMA embolization in their new systematic review and meta-analysis: doi.org/10.1016/j.jo...
- 💡Bottom line: TRA demonstrates no significant differences in hematoma recurrence, procedural time, or overall complications vs. TFA. #neurosurgery #neuroIR #SDH #TBI
- 💡TRA may offer benefits such as fewer access-site complications, faster recovery, and earlier ambulation compared to TFA. What is your preference? #surgery #neurology #stroke #brain
- Vertebrobasilar dolichoectasia (VBD) isn’t just a brain thing! Shimizu et al.’s study shows arteriopathies—like oversized arteries (arteriomegaly) & aneurysms—happen across the body. Let’s unpack it! www.sciencedirect.com/science/arti... 🧠🩺 #NeuroVascular #Neurology
- Key findings: VBD patients had bigger brain arteries (e.g., ICA: 6.7 vs. 3.8 mm in controls, P<0.0001) and 71% showed trunk vessel issues. Meta-analysis of 11 studies pegged high odds elsewhere—23% anterior circulation, 37% aorta, 43% coronary. #StrokeRisk #Science
- VBD’s root cause remodels arteries far beyond the brainstem, driving diffuse or focal ectasias. Shimizu’s work hints at a systemic link—could this reshape diagnosis & treatment? #MedicalResearch #VascularHealth
