Gísli
Scientist, clinician, cyclist, Spurs, SFGiants
#CureIPF
imperial.ac.uk/mtw-centre-fibrosin…
- Will REMAP-ILD contribute to understanding and improving outcomes for Multiple Long Term Conditions? I think so! @nihr.bsky.social @ukri.org @kerrijohannson.bsky.social @kaminskimed.bsky.social @actionpfcharity.bsky.social
- I tell ya Tammy Bruce is gonna be a 🌟! Her presser was quite the event especially from 6-10 minutes. 😅😅 #TammyIsAwesome www.youtube.com/live/oy2JOqH...
- Great to host Vidya Navaratnam MTWCentre. Her seminar places supportive care at centre stage! Raises really important questions about care at end of life & impact on survival and hospitalisations. Needs urgent further study! @kerrijohannson.bsky.social @kaminskimed.bsky.social
- Scammers playing on my ego! 🤣🤣 Just as well awards are not my motivation for doing science and medicine! #CureIPF
- Over yrs involved in #MedPublishing I have spent much time a) trying to obtain peer review & b) answering author complaints about delays due to lack of peer review. This invirtuous circle is getting worse. Should we a) dispense with peer review altogether or b) outsource to AI or c) something else?
- Found it strangely reassuring as I reflected on my recent exploration of Istanbul, London & Siena. The history & complexity of these wonderful places reassures me Europe will withstand current challenges & emerge stronger, more vibrant than ever. I hope random younger countries fare so well. 🙏🙏
- What happens if you get stuck in a room with nothing but a pen and paper? Feel free to send suggestions for more ideas to add to my picture representing the pathogenesis of ….
- I was asking myself why I and so many others found this so triggering! Then I realised it’s classic victim blaming, a common feature of misogyny and also used to suppress minorities with whom one might have beef.
- www.medpagetoday.com/opinion/faus... Interesting to see what the journals make of this. It will cause chaos @thelancet.bsky.social
- Not sure how this bad news passed us by from the end of 2024! Maybe we were preoccupied by other things?! 😱 www.fiercebiotech.com/biotech/amge...
- If JD Vance is so concerned about free speech I expect the US will stop banning books and allow all words to be used in research proposals?
- Disappointing news from Pliant on Friday. No news of detail but likely that DSMB noted a safety signal based on v. brief press release & prior data inhibiting avb6 integrins. 😭 Market reaction brutal! 😳 @kerrijohannson.bsky.social @kaminskimed.bsky.social
- You said offer remote cat sitting services! 😂
- Nice use of cycle lanes by Naughtons buses! 🙄
- And what’s happened since we wrote this? climate.nasa.gov/vital-signs/...
- We published ‘Climate change and lung health: the challenge for a new president’ 8 yrs ago encouraging the (then) new president to follow the steps of Thatcher and Reagan, change course and take bold action to fight climate change. It was true then. Even truer now. thorax.bmj.com/content/72/4...
- Am I the only person who thinks it’s gonna drive Trump to distraction that the only thing people will ever remember about yesterday’s inauguration is Elon’s Nazi salute? 🤔
- 100% agree UK access for people aged 65yr+ or 50yr+ with immune deficiency. This is not about population benefit/herd immunity it’s about staying healthier for longer. I would have it tomorrow if I was eligible.
- As I was saying: If you're eligible for a shingles vaccine, get it. If me saying "trust me, you don't want shingles in your eye" isn't enough, here's @drjengunter.bsky.social with much more: vajenda.substack.com/p/the-shingl...
- This is a super interesting study and may help explain why high rates of collagen degradation are associated with fibrosis coz collagen fragments are recycled NOT necessarily degraded. Kudos @tranejoan.bsky.social & team!
- Fascinating study from @tranejoan.bsky.social linking integrin-collagen binding, circadian control & endocytosis with IPF (@ipfdoc.bsky.social). Chang J, et al. Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis. Elife. 2025 Jan 15;13. PMID: 39812558
- Anti-fibrotic use associated with improved survival in IPF. Any data demonstrating this direct effect of drug, or is it consequence of improved delivery of care associated with the introduction of a new class of drugs? @kaminskimed.bsky.social @kerrijohannson.bsky.social @drdayjee.bsky.social
- Why we need fact checkers! ‘Free speech’ has consequences. www.bbc.co.uk/news/videos/...
- So sad that in the last 12 months Jasper and the Palisades have been lost to wildfire. Sadder still the conservative governor of Alberta blamed Liberal federal government & the Republican president-elect blamed Democratic governor, & so nothing will be done about what is really to blame. 😢😢
- Fab day at 13th Jules van den Bosch ILD symposium in Woerden (cute little 🇳🇱 town). Great talks from Sara Tomassetti 🇮🇹 describing distinctions in evolution from ILA-ILD (>20% radiological involvement), Coline van Moorsel 🇳🇱 on genetics in IPF (40% causal variants found in FPF in 🇳🇱)
- Really fab & thought provoking review which aligns with my current view of the pathogenesis of #IPF from Ashesh Chakraborty, Herbert Schiller & @staabweijnitz.bsky.social & team. 👏👏👏 mdpi-res.com/d_attachment...
- Both beautiful and terrifying at the same time! #DecemberDaffodils 😱😱
- Such an important figure. www.instagram.com/reel/DDK0Ak2...
- Interesting results phase 2b results out for deuterated Pirfenidone (Deupirfenidone) in #IPF with promising efficacy and tolerability profiles. news.puretechhealth.com/news-release...
- It’s been a long time coming but finally it’s out: Effect of nintedanib on circulating biomarkers, #SpoilerAlert it’s the epithelium (well CA125 anyway) publications.ersnet.org/content/erjo...
- So proud of Sam, the first #MTWCentre PhD student to graduate! #NeverInDoubt Smart, thoughtful, inquisitive and fun. The future is 🔆. Good luck Dr Moss 💫💫
- Spurs 3 up inside 20 mins. Anybody think we’ll hold onto the lead? 😅😅
- Delighted 2 share latest preprint evaluating fibrotic niche in #IPF using spatial transcriptomics & Hyperion mass cytometry. We believe it raises some interesting questions about IPF pathogenesis IPF. @nebanovich.bsky.social @kaminskimed.bsky.social www.biorxiv.org/content/10.1...
- Latest power calculation is in and the answer is n+1. IYKYK