Ben Engel
cellarchlab.com Univ. of Basel Biozentrum🇨🇭. Exploring molecular architecture inside cells with #CryoEM #TeamTomo. Plants and algae in a changing climate. ❄🔬 OF 🌿 4THE 🌍!
- Interesting thread 🧵 from @georghochberg.bsky.social dissecting the evolution of nitrogenases from cofactors of methane-producing enzymes. The “molecular paleontology” possible with modern technology is so cool. 🧪🧶🧬
- How does nature build a light-powered water-splitting machine that makes life on our planet possible?🌍 …very carefully and step by step!🏗️🚧 Congrats to @schullerjm.bsky.social and collabs on this exciting structure of a Photosystem II assembly intermediate! 🧪🧶🧬🌾🔬
- Reposted by Ben EngelRibosomes for everyone
- “The Website” is here! It can be intimidating getting into analysis of #CryoET data, and software is evolving all the time👩💻🚀. @phaips.vd.st & @florentwaltz.bsky.social put our lab’s workflows into an online guide. We hope this helps lower the bar to joining #TeamTomo. Feedback much appreciated! 🧪🧶🧬🔬
- Hey #TeamTomo, Ever been in need of a tutorial about the fundamentals of cryo-electron tomography? From preprocessing raw frames to high-res subtomogram averaging? That's why @florentwaltz.bsky.social and I made this website! tomoguide.github.io Follow the thread 1 /🧵 #CryoET #CryoEM 🔬🧪
- Thanks a lot @arianebriegel.bsky.social for visiting the @biozentrum.unibas.ch and telling us about your amazing #TeamTomo science. The squid 🦑 bacterial symbiosis cryo-lift out is super cool!! 🤩 #FIBtheWorld 🧪🧶🧬🌊
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- Let’s average all the things! Visual proteomics time?😉 #TeamTomo 🧪🧶🧬🔬
- To all #ChlamyDataset enthusiasts, here is a script that lets you directly import the pre-processed results from EMPIAR-11830 into #RELION v5 for subtomogram averaging: github.com/Chromatin-St... #Chlamydomonas #TeamTomo #CryoET #OpenSoftwareAcceleratesScience
- So sad and total barf🤮. DOGE wiped them out and the NOAA account is now a propaganda machine 🧪🌍🌊
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- Reposted by Ben Engel[Not loaded yet]
- What's new in #MemBrain v2? Check out the thread from @lorenzlamm.bsky.social below🧵👇. The software now provides a end-to-end pipeline that segments membranes, finds embedded membrane proteins, and quantifies their organization. #TeamTomo please try it out👩💻. We eagerly await your feedback! 🧪🧶🧬🌾🦠🔬
- 🦠🧠 MemBrain update! 🧠🦠 We’ve updated our preprint! It now covers the full MemBrain v2 pipeline for end-to-end membrane analysis in #CryoET: segmentation, particle picking, and spatial statistics. 🔗 Preprint: doi.org/10.1101/2024... 🔗 Code: github.com/CellArchLab/... 🧵(1/6) #TeamTomo
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- Some eye-catching #TeamTomo work here. Congrats to @kfreeman.bsky.social and all the authors! 🧪🧶🧬🔬
- A very shiney #cryoEM structure of the MCR Activation Complex from anaerobic archaea. It’s the complex that makes methane. Or as I prefer to call it— the Fart Complex 💨. Big congrats to @schullerjm.bsky.social and the whole team! 🧪🧶🧬🔬🌊🌍 #ArchaeaSky
- “Organelle Hijacking” is my new favorite scientific term. Beautiful 3D FIB-SEM🔬 work on marine plankton by @johandecelle.bsky.social and crew! The #CO2 fixing pyrenoids are massive in the stolen plastids 🧪🌊
- “It’s a me, Golgi!” 🧪🇮🇹
- It’s been a very inspirational #EMBOclimateResilience workshop so far. I’m looking forward to the table discussions starting tomorrow. Here are some fancy highlights from the opening night 🧪🍿
- “No Water, no Life. No Blue, no Green.”💙💚 @floravincent.bsky.social from @embl.org revealing the beauty of diatom symbiotic interactions, which enable these globally important phytoplankton to adapt to environmental stresses and pollutants. Such cool science here at #EMBOclimateResilience 🧪🌊🌍
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- Reposted by Ben Engel[Not loaded yet]
- Cool result from @becklab.bsky.social, combining years of advances in both stem cell biology and #TeamTomo. That it is now possible to mutate part of the NPC and then use #CryoET to see how pores are structurally disturbed upon differentiation into neurons… kinda mind blowing where we are now 🧪🧶🧬🔬
- So excited to be here at #EMBOclimateResilience, a cool new meeting integrating cell and planetary scales. Inspiring first night keynotes by Jeremy Farrar (chief scientist of @who.int) and Pam Silver. Thanks for organizing, @monicabettencourt.bsky.social! 🧪🌊🌾🌍
- #TeamTomo is going to be all over chromatin structure and organization in the next years. Beautiful efforts like this are only the beginning! 🧪🧶🧬🔬
- Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social, @marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social 🔗 Preprint here tinyurl.com/3a74uanv
- There’s more than one way to slice a lamella. Try an Ion Knife ⚡️🔪 #TeamTomo 🧪🧶🧬
- Whelp… there goes the MemBrain. Thanks for hosting Lorenz, @dtegunov.bsky.social & @alisterburt.bsky.social 🧠🦀 #TeamTomo🧪🧶🧬
- All aboard the time machine!🕰️ I love the topic of how life co-evolved with (and drove) the changing geochemistry of our planet. Very interesting study here about how aerobic respiration may have evolved before (and helped enable) the Great Oxidation Event 2.4 billion years ago 🧪🧶🧬🌊🌾🌍
- That's a fancy video. I was certainly surprised to see the Very Important Protein in Plants discovered in a tropical jungle🌴😅. It's pure marketing ofc (The Krios: Now in Black), but I do like the messaging about discovering the molecular world all around us-- including plants and cyanobacteria🧪🧶🧬🔬🌾🌊
- Curious about the intersection of math, physics, and biology? Check out this cool masters at the @biozentrum.unibas.ch (with scholarships!) 🧪🧑🎓🧑🔬
- Apply now for our international Master of Science in Physics of Life @biozentrum.unibas.ch @unibasel.ch! Scholarships available. More information: www.biozentrum.unibas.ch/education/de... #Master #Students #Research #Physics #Mathematics #ComputerScience #Engineering #Basel #Switzerland
- Reposted by Ben EngelA little late to the party (I was out last week), but so happy to promote this paper and its animated cover in @science.org www.science.org/doi/10.1126/...
- In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion. Learn more in this week's issue: scim.ag/3FA3Ygq
