Brain Communications
Open Access sister journal to Brain. 🧠🧠🧠
Proceeds go to Guarantors of Brain Charity to support the translational neuroscience community.
Join our community of authors, reviewers, prize winners!
- Basgaran et al. reported that in countries with high Alzheimer’s disease (AD) incidence, the composition of gut microbiome significantly differs. Using machine learning, they predicted population incidence of AD based on gut microbiome profile. Read at: buff.ly/F45d3QD.
- Sakiyama et al. report that metagenomic next-generation sequencing (mNGS) on brain tissue improves diagnosis of CNS diseases, identifying pathogens in 21.2% and ruling out infection in 42.4% of cases. Please read at: buff.ly/YkXzG0O
- Marchiotto et al. report that combining A-tDCS with physical activity enhances motor cortex plasticity in mice, boosting neuron activation, connectivity, and spine density. Please read at: buff.ly/6e0lEc9
- Strik et al. report that visual snow patients show altered brain connectivity, with stronger cortical links but weaker connections to deep grey matter, tied to symptom disruptiveness. Please read at: buff.ly/BXOLHqS
- Prochnow et al. report that Gilles de la Tourette Syndrome patients show stronger theta but weaker alpha activity during response inhibition, revealing disrupted perception-action processes. Please read at: buff.ly/fYtb526
- Jerele et al. report on the potential of the Cholinergic Pathway Hyperintensities Scale (CHIPS) to identify cholinergic white matter damage in Lewy body dementia, linked to frontal atrophy and vascular health. Please read at: buff.ly/vDYXTZz
- Zhang et al. report that cerebellar and corticospinal white matter integrity predicts aphasia severity post-stroke, revealing new biomarkers for language recovery. Please read at:https://buff.ly/C4nT9Qh
- Thielen et al. report that post-stroke sensory hypersensitivity links to lesions in the putamen, thalamus, amygdala, insula, and related white matter tracts. Please read at: buff.ly/Lybj1Xo
- Chamoun et al. report that high-sensitive cardiac troponin T (hs-cTnT) in ALS patients correlates with lower motor neuron involvement on EMG and disease spread. Please read at: buff.ly/XytKPdY
- McKay et al. report that increased healthcare use 1–10 years before pediatric-onset MS suggests a prodromal phase, with ill-defined symptoms and skin issues prevalent. Please read at: buff.ly/kMp6Lng
- Imokawa et al. report that machine learning reveals two myotonic dystrophy type 1 brain atrophy subtypes - cortical and subcortical, linked to cognitive decline and brain development. Please read at: buff.ly/f1Mfn1K
- Kremen et al. report that low-frequency ANT-DBS shows greater seizure reduction, improved sleep, and memory in temporal lobe epilepsy, suggesting potential for optimised neuromodulation therapy. Please read at: buff.ly/sBgZwrH
- Basgaran et al. report gut microbiome diversity linked to Alzheimer’s disease incidence, with species like E. coli and Akkermansia showing protective effects. Machine learning predicts disease risk. Please read at: buff.ly/QdocWpe
- Moresco et al. report elevated circulating cell-free mitochondrial DNA in NT1 patients, linking neuroinflammation, mitochondrial dysfunction, and altered sleep architecture. Please read at: buff.ly/H3kyDi0
- Igawa et al. report key brain regions linked to central & non-central post-stroke pain, helping improve diagnostics & personalised treatments for pain management. Please read at: buff.ly/h30Oiu0
- Our scientific editor Dr. Marescotti shares highlights from the Brain Conference 2025, in the editorial of Volume 7 Issue 3 of Brain Communications. Please read at: buff.ly/pVutPgl @manuelamarescotti.bsky.social
- Rashid et al. report that schizophrenia impairs brain activity during movement prep, especially for self-actions, highlighting disrupted predictive processing tied to symptom severity. Please read at: buff.ly/COJgExS
- Papadelis et al. report that noninvasive EEG/MEG can distinguish pathological from physiological high-frequency oscillations, aiding epilepsy diagnosis and surgical planning in children. Please read at: buff.ly/WTNbyGc
- Campins-Romeu et al. report that bilateral staged MRI-guided focused ultrasound thalamotomy significantly reduces tremor and improves quality of life in medication-refractory Essential Tremor patients. Please read at: buff.ly/xizCz87
- Sukhonpanich et al. establish age and sex-specific reference ranges for serum neurofilament light chain in healthy Thai adults, aiding clinical use in detecting axonal injury. Please read at: buff.ly/sTXf5Sl
- Lin et al. examine thrombolytics like tenecteplase, which offer improved stroke treatment with better dosing, safety, and efficacy, advancing therapy beyond traditional time windows. Please read at: buff.ly/Phi8KCY
- Guan et al. report that vascular risk factors are strongly associated with early cognitive and behavioral symptoms preceding dementia in older adults. Please read at: buff.ly/jkg0TbF
- Dias et al. report that transcriptome analysis in Portuguese women reveals parathyroid hormone receptor genes as promising migraine biomarkers. Please read at: buff.ly/5URYcHW
- What are potential barriers to preregistering neuropsychological research? This review maps out key issues and routes to achieving the key objectives of preregistration when studying rare or hard-to-access populations. Read at: buff.ly/0AmdbGd @britishneuropsych.bsky.social @rjbinney.bsky.social
- Knudtzon et al. report that in Alzheimer’s, amyloid-positive females show distinct immune profiles of lower inflammation but stronger links to neurodegeneration markers. Please read at: buff.ly/OFgiWQk
- Du et al. report that white matter disease & amyloid in Alzheimer’s accumulate independently. However together, they accelerate cognitive decline. Please read at: buff.ly/dUsiB63
- Rauch et al. provide the first quantitative evidence, that Low Grade Gliomas do not primarily grow along white matter tracts. Instead, they follow an ontogenetically and anatomically driven growth pattern, challenging current models of tumor progression. Please read at: buff.ly/xtF5iUa
- Räuber et al. report that multidimensional flow cytometry may enable earlier, more accurate diagnosis of autoimmune limbic encephalitis via immune profiling. Please read at: buff.ly/JT8AROl
- Day 3: @braincomms.bsky.social and @brain1878.bsky.social up for the last day, we are waiting for you 😆 #bna2025
- Décarie-Labbé et al. report that early brain activation anomalies predict cognitive decline in Alzheimer’s risk, offering a powerful tool for early detection. Please read at: buff.ly/PajcgsC #Alzheimers
- McNally et al. report that mild perinatal brain injury causes delayed neuronal death despite normal early function, highlighting a window for neuroprotective therapy. Please read at: buff.ly/Xo2EGXl
- #BNA2025 Day 2: @braincomms.bsky.social and @brain1878.bsky.social booth is up again, stop by to say hi! #neuroscience
- Reposted by Brain Communications[Not loaded yet]
- Skattebøl et al. report that deep learning predicts brain age in MS more accurately than traditional ML and resists scanner variability. Please read at: buff.ly/CqHOEG6 #MS
- Li et al. report that congenital visual and hearing impairments reshape brain function, showing reduced connectivity and dysrhythmic activity, suggesting a triple network anomaly. Please read at: buff.ly/Z8wcucj
- Meet the editors-in-chief of @brain1878.bsky.social and @braincomms.bsky.social today at 1pm at our booth (stand 22) #bna2025 @tspiresjones.bsky.social @masudhusain.bsky.social 😀
- @brain1878.bsky.social and @braincomms.bsky.social booth is up at #BNA2025 stop by to learn more about our journals 😃 #neuroscience #liverpool
- Tsagkaris, McClelland et al. report that in paediatric dystonia, regional patterns of brain glucose metabolism, measured with PET imaging, are related to neurophysiological measures of functional integrity of motor and sensory neural pathway. Please read at: buff.ly/IZRDCPx
- Researchers from the Danish Headache Center report chronic migraine, daily headache & prior treatment failures reduce erenumab efficacy for migraine. Older age linked to better outcomes. Severe phenotypes linked to delayed response. Please read at: buff.ly/teJLQH3 @hmru_cph
- Shawa et al. report that Parkinson’s disease shows 4 subtypes based on MRI-defined atrophy patterns. Atrophy severity, not location, differentiates clinical progression. Please read at: buff.ly/PXFefbU @ShawaZeena @NeilOxtoby @rimonaweil
- Are you attending the #BNA2025 Festival in Liverpool this April? We would love to hear from you! Reach out to us on Bluesky by tagging @braincomms.bsky.social in your posts. #BNA2025 #NeuroTwitter #Neuroscience
- Broberg et al. report that spoken language reflects white matter microstructure—not lesion volume—in cerebrovascular disease, highlighting diffusion MRI's role in cognitive assessment. Please read at: buff.ly/uxBuMwo @Rob_Bartha @lcanresearch @ONDRISTUDY @WesternU @SchulichMedDent
- Arora et al. report on the use of flies as a model organism to explore the biological mechanisms of, and genetic predisposition to neurodegeneration. Please read at: buff.ly/WxE74pW @petrosligoxygakis.bsky.social
- Are you attending the #BNA2025 Festival in Liverpool this April? We would love to hear from you! Reach out to us on Bluesky by tagging @braincomms.bsky.social in your posts. #BNA2025 #NeuroTwitter #Neuroscience
- Nejedly et al. report that a graph neural network using iEEG, MRI & electrode topology predicts epilepsy surgery targets, outperforming standard models—promising tool for DRE planning. Please read at: buff.ly/oymy1Om
- Spruyt et al. report that even before symptoms appear, tau buildup in early Alzheimer’s disrupts brain networks. EEG shows early small-world disintegration. Please read at: buff.ly/aSlcjZp @Lab_Cog_Neu_KUL @laurespruyt
- Zhang et al. report that in rural China, cerebral small vessel disease is highly prevalent in older adults. Age, hypertension & heart disease are key risk factors. Please read at: buff.ly/gc4e9an
- Flanagan et al. report that 7 Tesla functional magnetic resonance imaging suggests a role for anterior nuclei of the thalamus in prospective memory. Please read at: buff.ly/2HqpzPu @NeuroCyberLab
- Calling all #BrainCommunications authors presenting at #BNA2025 in Liverpool this April! 🎉 We’d love to hear from you. Tag @braincomms.bsky.social in your posts to reach out to us on Bluesky. #BNA2025 #NeuroTwitter #Neuroscience
- Dahlin et al. report that genetic variants can predict seizure response to ketogenic diet in kids with epilepsy—transporters respond best, structural genes worst. Please read at: buff.ly/rjHiHgw
- Coles et al. reveal how α-synuclein aggregation and lipid changes contribute to neurodegeneration in Parkinson’s disease and related Lewy body diseases using Raman spectroscopy and machine learning. Please read at: buff.ly/YZCPGww #Parkinsons #Neuroscience #Synuclein @akhundakar.bsky.social
