Shicheng Guo

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  Shicheng Guo shihcheng.bsky.social · May 11
  Discover MMEASE 2.0: A groundbreaking workflow enhancing single-cell metabolomics, shifting research focus from bulk to SCM for better insights. PMID:40308213, Nucleic Acids Res 2025, @NAR_Open doi.org/10.1093/nar/gkaf363 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

  https://doi.org/10.1093/nar/gkaf363

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  Shicheng Guo shihcheng.bsky.social · May 7
  Implantable & wearable biosensors revolutionize kidney health by enhancing 24/7 monitoring of biomarkers like creatinine. 🔬📈 PMID:40301646, Nat Rev Nephrol 2025, @NatRevNeph doi.org/10.1038/s41581-025-… #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
  

  Implantable bioelectronics and wearable sensors for kidney health and disease | Nature Reviews Nephrology

  Established clinical practices for monitoring kidney health and disease — including biopsy and serum biomarker analysis — suffer from practical limitations in monitoring frequency and lack adequate sensitivity for early disease detection. Engineering advances in biosensors have led to the development of wearable and implantable systems for monitoring of kidney health. Non-invasive microfluidic systems have demonstrated utility in the detection of kidney-relevant biomarkers, such as creatinine, urea and electrolytes in peripheral body fluids such as sweat, interstitial fluid, tears and saliva. Implantable systems may aid the identification of early transplant rejection through analysis of organ temperature and perfusion, and enable real-time assessment of inflammation through the use of thermal sensors. These technologies enable continuous, real-time monitoring of kidney health, offering complementary information to standard clinical procedures to alert physicians of changes in kidney h

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  Shicheng Guo shihcheng.bsky.social · May 7
  Looks like we’re about to hit 1,000 followers on Bluesky tonight! 🚀 Grateful for the support from the AI + biomedicine community 💡 If you’re passionate about translating genomics into real-world impact, let’s connect. #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
  
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  Shicheng Guo shihcheng.bsky.social · May 7
  Explore how neural oscillations align with music, impacting pitch, harmony, rhythm, and emotion. Discover deeper dynamics! 🎶🧠 PMID:40102614, Nat Rev Neurosci 2025, @NatRevNeurosci doi.org/10.1038/s41583-025-… #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
  

  Musical neurodynamics | Nature Reviews Neuroscience

  A great deal of research in the neuroscience of music suggests that neural oscillations synchronize with musical stimuli. Although neural synchronization is a well-studied mechanism underpinning expectation, it has even more far-reaching implications for music. In this Perspective, we survey the literature on the neuroscience of music, including pitch, harmony, melody, tonality, rhythm, metre, groove and affect. We describe how fundamental dynamical principles based on known neural mechanisms can explain basic aspects of music perception and performance, as summarized in neural resonance theory. Building on principles such as resonance, stability, attunement and strong anticipation, we propose that people anticipate musical events not through predictive neural models, but because brain–body dynamics physically embody musical structure. The interaction of certain kinds of sounds with ongoing pattern-forming dynamics results in patterns of perception, action and coordination that we coll

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