Karolinska Institutet
Science news from the medical university Karolinska Institutet (KI) in Sweden. Our vision is to advance knowledge about life and strive towards better health for all. ki.se
- Forskningen kräver fria internationella samarbeten - debattinlägg av Karolinska Institutets rektor Annika Östman Wernerson och prorektor Martin Bergö i @di.se di.se/debatt/forskningen-kraver-fria-internationella-samarbeten/
- A study published in @cp-devcell.bsky.social points to new treatment strategies for the #childhoodcancer #neuroblastoma. Researchers have identified key transcription factor ‘switches’ that can be targeted to lock the cancer into a less aggressive state. #CancerResearch 🧪 doi.org/10.1016/j.de...
- #Antibiotics administered together with the enzyme endolysin from bacteriophages protect against infection by resistant bacteria in all bodily organs in mice – including the brain, which antibiotics alone have difficulty reaching. Study published in Molecular Medicine 🧪 news.ki.se/researchers-...
- Researchers have revealed how tetracycline antibiotics impair T cell function. The study raises important considerations for antibiotic therapy and developing new molecules to better distinguish pathogens and host cells. Published in Nature Communications. 🧪
- Marcus Buggert and colleagues have identified biomarkers in the blood associated with symptoms of #LongCOVID, particularly severe respiratory problems. The discovery, published today in Nature Immunology, can pave the way for future diagnosis and treatment. 🧪 #PostCOVID news.ki.se/long-covid-b...
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- KI researchers have engineered #extracellularvesicles to facilitate the delivery of therapeutic proteins and RNA, including gene editors, to cells. The method, presented in @natcomms.nature.com, shows promising results in animal studies. 🧪 #genetherapy #biotech news.ki.se/new-technolo...
- A new study published in Intensive Care Medicine shows that intravascular cooling is more effective than surface cooling for patients who have suffered cardiac arrest outside of a hospital. The research could have significant implications for future treatments 🧪 link.springer.com/article/10.1...
- Researchers have identified a new mechanism where circular RNA plays a crucial role in wound healing, which could lead to new therapies to improve wound healing and reduce scarring. The study was published in Advanced Science 🧪 news.ki.se/new-discover...
- The incidence of pneumococcal haemolytic uremic syndrome has increased tenfold among Swedish children in recent years. This coincides with a change in the National Immunisation program from pneumococcal #vaccine PCV13 to PCV10 that protects against fewer strains 🧪 #Pediatrics doi.org/10.1001/jama...
- A recent study found that phosphatidylethanol (PEth) levels can distinguish between different types of fatty liver disease and predict the risk of major liver outcomes. Published in @jhepatology.bsky.social by @liverepi.bsky.social et al 🧪#medsky www.sciencedirect.com/science/arti...
- A newly published Cochrane review reveals significant gaps in the clinical rating scales used to assess pain in newborn babies, highlighting the urgent need for improved tools and global collaboration 🧪 www.cochranelibrary.com/cdsr/doi/10....
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- A new study shows how a small antibody fragment can block fertilisation by targeting a key protein on the surface of the egg. This discovery brings a non-hormonal contraceptive one step closer to reality. Published in @pnas.org. Research by @lucajovine.bsky.social et al 🧪 news.ki.se/new-step-tak...
- Researchers have identified guinea pig as a promising model for studying the development of human embryos. A study in Nature Cell Biology shows that guinea pig embryos share many characteristics with humans, which may open up new research opportunities in fertility 🧪 news.ki.se/guinea-pigs-...
- A new study reveals that days with both high air pollution and extreme heat substantially raise the risk of death in Indian cities more than either factor alone. 🧪 Published in in Environment International. www.sciencedirect.com/science/arti...
- In a study in @science.org, researchers @anderssonlab.bsky.social have used a new method to study how the nervous system and inner ear are formed in a mouse embryo. The discovery could provide important insights for future treatment of #hearingloss 🧪 #neuroscience news.ki.se/new-method-r...
- A new study in Nature Medicine shows that researchers have demonstrated how specific biomarkers in the blood can predict the development of dementia up to ten years before diagnosis among older adults living independently in the community 🧪 news.ki.se/blood-test-m...
- The antimalarial dihydroartemisinin-piperaquine (DHA-PPQ) loses its prophylactic post-treatment protection upon repeated #malaria episode treatments, as it selects parasites carrying mutations in the plasmepsin 3 gene, finds a study published in @naturecomms.bsky.social 🧪 doi.org/10.1038/s414...
- The Swedish National Patient Register, NPR, has good diagnostic accuracy for most diagnoses and very good for surgical procedures, according to a new review. The sensitivity is lower. Missingness is higher among private healthcare providers 🧪 #Epidemiology #MedicalResearch doi.org/10.1007/s106...
- KI researchers have shown that material from nasal lavage provides a basis for assessing #COPD, chronic obstructive pulmonary disease. The study, published in the Journal of Allergy and Clinical Immunology, could lead to a simple diagnostic method 🧪 news.ki.se/protein-in-t...
- KI researcher Alexander Espinosa and colleagues have developed a novel method for genetic research, BLU-VIPR, that allows researchers to control the gene-editing tool #CRISPR using light. The study is published in @narjournal.bsky.social 🧪 news.ki.se/new-light-co...
- Certain widely used drug combinations may either slow down or worsen the progression of Alzheimer’s disease, but their effects differ between sexes. A new study published in the journal Alzheimer’s & Dementia highlights these critical findings 🧪 news.ki.se/common-multi...
- In a new study, researchers have shown that interval cancers, which are detected between two screening sessions, account for a significant proportion of breast cancer cases and that certain risk factors may increase the likelihood of developing this type of cancer 🧪 news.ki.se/three-out-of...
- A study in @nature.com by researchers at KI, @scilifelab.se and others reveals a new stress response mechanism in cells called split ISR (s-ISR). This may have implications for the treatment of #cancer and neurodegenerative diseases like leukodystrophies 🧪 #CellBiology www.nature.com/articles/s41...
- Researchers have discovered a new mechanism behind blood vessel damage in type 2 diabetes. The study shows that small vesicles from red blood cells can transfer harmful signal molecules to the blood vessels and impair their function 🧪 news.ki.se/new-mechanis...
- One in eight patients admitted to hospitals is critically ill, and most of these patients are cared for outside intensive care units, according to a new study from three different countries published in BMJ Global Health by @carlottoschell.bsky.social and colleagues 🧪 news.ki.se/one-in-eight...
- A new study in @natmedicine.bsky.social by KI professor @elisabetsv.bsky.social and colleagues shows that the endometrium of women with #PCOS differs in terms of both the composition of individual cells and gene expression. The results open the door to new treatments 🧪 news.ki.se/cell-atlas-o...
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- Patients who have been treated for #heartfailure and experience an improvement of their pump function, are still at higher risk of heart-related death or hospitalisation if they stop taking heart failure medications, according to a new KI study published in Circulation 🧪 news.ki.se/continued-me...
- Researchers have identified a mechanism that improves the treatment of ischemic stroke. The study, in Journal of Clinical Investigation, shows that the growth factor PDGF-CC and its receptor PDGFRα play a crucial role in scar formation after a stroke 🧪 Photo: Getty Images news.ki.se/new-findings...
- A new KI study published in @commsmed.bsky.social shows that females in Sweden wait longer for #cataract surgery than males – on average 64 days vs. 60 days. Despite small differences, this points to potential healthcare inequities. 🧪 #HealthEquity doi.org/10.1038/s438...
- A new study reveals that a significant proportion of people living with HIV on long-term antiretroviral therapy remain at risk of immune and metabolic complications despite successful viral suppression. news.ki.se/study-reveal...
